Luna Musib: search on Z-Library

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1

Application of a Novel ‘Make and Test in Parallel’ Strategy to Investigate the Effect of Formulation on the Pharmacokinetics of GDC-0810 in Healthy Subjects

Cheeti, Sravanthi, Hou, Hao Helen, Nelson, Eric, Walker, Helen, Chen, Buyun, Morley, Roland, Gates, Mary, Musib, Luna, Girish, Sandhya, Sahasranaman, Srikumar, Liu, Lichuan

Journal:

Pharmaceutical Research

Year:

2018

Language:

english

File:

PDF, 1.47 MB

english, 2018

2

Safety of an IV formulation of carbamazepine

Jeannine M. Conway, James R. White, Angela K. Birnbaum, R. Eugene Ramsay, Page B. Pennell, John O. Rarick, Luna Musib, Ilo E. Leppik, James C. Cloyd

Journal:

Epilepsy Research

Year:

2009

Language:

english

File:

PDF, 112 KB

english, 2009

3

A Phase II Multicenter Study of Two Different Dosages of Pemetrexed Given in Combination With Cyclophosphamide as First-Line Treatment in Patients With Locally Advanced or Metastatic Breast Cancer

Dittrich, Christian, Solska, Ewa, Manikhas, Alexey, Eniu, Alexandru, Tjulandin, Sergei, Anghel, Rodica, Musib, Luna, Frimodt-Moller, Bente, Liu, Yushan, Krejcy, Kurt, Láng, István

Journal:

Cancer Investigation

Year:

2012

Language:

english

File:

PDF, 224 KB

english, 2012

4

MEK inhibitors beyond monotherapy: current and future development

E Templeton, Ian, Musib, Luna

Journal:

Current Opinion in Pharmacology

Year:

2015

Language:

english

File:

PDF, 353 KB

english, 2015

5

Calibrating the in vitro-in vivo correlation for OATP mediated drug-drug interactions with rosuvastatin using static and PBPK models

Sane, Rucha, Cheung, Kit Wun Kathy, KovÃ¡cs, PÃ©ter, Farasyn, Taleah, Li, Ruina, Bui, Annamaria, Musib, Luna, Kis, Emese, Plise, Emile, GÃ¡borik, Zsuzsanna

Journal:

Drug Metabolism and Disposition

Year:

2020

File:

PDF, 1.17 MB

2020

6

PD4-3-4: Correlation of pemetrexed (PEM) NSCLC exposure-response relationships (ERRs) to clinical study results from western and Japanese patient populations

Latz, Jane, Adachi, Susumu, Symanowski, James, Nakagawa, Kazuo, Tamura, Tokuhiro, Hanna, Nasser, Cullen, Michael, Falcoz, Christine, Musib, Luna, Calvert, Hilary

Journal:

Journal of Thoracic Oncology

Year:

2007

Language:

english

File:

PDF, 173 KB

english, 2007

7

Correction to: Application of a Novel ‘Make and Test in Parallel’ Strategy to Investigate the Effect of Formulation on the Pharmacokinetics of GDC-0810 in Healthy Subjects

Cheeti, Sravanthi, Hou, Hao Helen, Nelson, Eric, Walker, Helen, Chen, Buyun, Morley, Roland, Gates, Mary, Musib, Luna, Girish, Sandhya, Sahasranaman, Srikumar, Liu, Lichuan

Journal:

Pharmaceutical Research

Year:

2018

Language:

english

File:

PDF, 887 KB

english, 2018

8

Safety, Tolerability, QTc Evaluation, and Pharmacokinetics of Single and Multiple Doses of Enzastaurin HCl (LY317615), a Protein Kinase C-β Inhibitor, in Healthy Subjects

Welch, Pamela A., Sinha, Vikram P., Cleverly, Ann L., Darstein, Christelle, Flanagan, Shawn D., Musib, Luna C.

Journal:

Journal of Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 250 KB

english, 2007

9

Effect of Hepatic Impairment on Cobimetinib Pharmacokinetics: The Complex Interplay Between Physiological Changes and Drug Characteristics

Cheeti, Sravanthi, Deng, Yuzhong, Chang, Ilsung, Georgescu, Isabela, Templeton, Ian, Choong, Nicholas, Cheung, Kit Wun Kathy, Girish, Sandhya, Musib, Luna

Journal:

Clinical Pharmacology in Drug Development

Year:

2020

File:

PDF, 589 KB

2020

10

A survey of new oncology drug approvals in the USA from 2010 to 2015: a focus on optimal dose and related postmarketing activities

Lu, Dan, Lu, Tong, Stroh, Mark, Graham, Richard A., Agarwal, Priya, Musib, Luna, Li, Chi-Chung, Lum, Bert L., Joshi, Amita

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 2.98 MB

english, 2016

11

Pediatric Dose Selection and Utility of PBPK in Determining Dose

Templeton, Ian E., Jones, Nicholas S., Musib, Luna

Journal:

The AAPS Journal

Year:

2018

Language:

english

File:

PDF, 695 KB

english, 2018

12

Pharmacokinetic evaluation of platinum derived from cisplatin administered alone and with pemetrexed in head and neck cancer patients

Pol M. Specenier, Tudor Ciuleanu, Jane E. Latz, Luna C. Musib, Christelle L. S. Darstein, Jan B. Vermorken

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2009

Language:

english

File:

PDF, 341 KB

english, 2009

13

A phase Ib open-label dose escalation study of the safety, pharmacokinetics, and pharmacodynamics of cobimetinib (GDC-0973) and ipatasertib (GDC-0068) in patients with locally advanced or metastatic solid tumors

Shapiro, Geoffrey I., LoRusso, Patricia, Cho, Daniel C., Musib, Luna, Yan, Yibing, Wongchenko, Matthew, Chang, Ilsung, Patel, Premal, Chan, Iris T., Sanabria-Bohorquez, Sandra, Meng, Raymond D., Bende

Journal:

Investigational New Drugs

Year:

2020

File:

PDF, 1.48 MB

2020

14

Pemetrexed combined with paclitaxel: a dose-finding study evaluating three schedules in solid tumors

Axel-R. Hanauske, Herlinde Dumez, Martine Piccart, Emine Yilmaz, Tobias Graefe, Thierry Gil, Lorinda Simms, Luna Musib, Ahmad Awada

Journal:

Investigational New Drugs

Year:

2009

Language:

english

File:

PDF, 485 KB

english, 2009

15

Vismodegib Efficacy in Advanced Basal Cell Carcinoma Maintained With 8-Week Dose Interruptions: A Model-Based Evaluation

Chanu, Pascal, Musib, Luna, Wang, Xin, Cheeti, Sravanthi, Girish, Sandhya, Bruno, Rene, Lu, Tong, Reddy, Josina, Jin, Jin Y., Caro, Ivor

Journal:

The Journal of Investigative Dermatology

Year:

2020

File:

PDF, 394 KB

2020

16

Determination of cobimetinib in human plasma using protein precipitation extraction and high-performance liquid chromatography coupled to mass spectrometry

Deng, Yuzhong, Musib, Luna, Choo, Edna, Chapple, Matthew, Burke, Sarah, Johnson, James, Eppler, Steve, Dean, Brian

Journal:

Journal of Chromatography B

Year:

2014

Language:

english

File:

PDF, 431 KB

english, 2014

17

Effects of enzastaurin and its metabolites on the QT interval in cancer patients

Welch, Pamela A., Ng, Wee Teck, Darstein, Christelle L., Musib, Luna, Lesimple, Thierry

Journal:

Journal of Clinical Pharmacology

Year:

2016

Language:

english

File:

PDF, 992 KB

english, 2016

18

Evaluation of Cytochrome P450 3A4-Mediated Drug–Drug Interaction Potential for Cobimetinib Using Physiologically Based Pharmacokinetic Modeling and Simulation

Budha, Nageshwar R., Ji, Tao, Musib, Luna, Eppler, Steve, Dresser, Mark, Chen, Yuan, Jin, Jin Y.

Journal:

Clinical Pharmacokinetics

Year:

2016

Language:

english

File:

PDF, 1.05 MB

english, 2016

19

Exposure-Response-based Product-Profile-driven Clinical Utility Index for Ipatasertib Dose Selection in Prostate Cancer

Zhu, Rui, Poland, Bill, Wada, Russ, Liu, Qi, Musib, Luna, Maslyar, Daniel, Cho, Eunpi, Yu, Wei, Ma, Han, Jin, Jin Yan, Budha, Nageshwar

Journal:

CPT: Pharmacometrics & Systems Pharmacology

Year:

2019

File:

PDF, 573 KB

2019

20

Absolute Bioavailability and Effect of Formulation Change, Food, or Elevated pH with Rabeprazole on Cobimetinib Absorption in Healthy Subjects

Musib, Luna, Choo, Edna, Deng, Yuzhong, Eppler, Steve, Rooney, Isabelle, Chan, Iris T., Dresser, Mark J.

Journal:

Molecular Pharmaceutics

Year:

2013

Language:

english

File:

PDF, 1.38 MB

english, 2013

21

Carboplatin and Paclitaxel in Combination With Oral Enzastaurin in Advanced Ovarian or Primary Peritoneal Cancer

Vergote, Ignace, Amant, Frederic, Oskay-Öezcelik, Gülten, Musib, Luna, Michel, Anne-Laure, Darstein, Christelle, Kania, Marek, Bauknecht, Thomas, Sehouli, Jalid

Journal:

International Journal of Gynecological Cancer

Year:

2009

Language:

english

File:

PDF, 878 KB

english, 2009

22

A phase I safety, tolerability, and pharmacokinetic study of enzastaurin combined with capecitabine in patients with advanced solid tumors

Camidge, D. Ross, Gail Eckhardt, S., Gore, Lia, OʼBryant, Cindy L., Leong, Stephen, Basche, Michelle, Holden, Scott N., Musib, Luna, Baldwin, John, Darstein, Christelle, Thornton, Donald, Finn, Richar

Journal:

Anti-Cancer Drugs

Year:

2008

Language:

english

File:

PDF, 161 KB

english, 2008

23

Population pharmacokinetics and dosing implications for cobimetinib in patients with solid tumors

Han, Kelong, Jin, Jin Y., Marchand, Mathilde, Eppler, Stephen, Choong, Nicholas, Hack, Stephen P., Tikoo, Nalin, Bruno, Rene, Dresser, Mark, Musib, Luna, Budha, Nageshwar R.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2015

Language:

english

File:

PDF, 11.18 MB

english, 2015

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